Cytokine & Growth Factor Reviews RSS feed: Articles in Press. Cytokine & Growth Factor Reviews publishes thought-provoking articles (critical reviews, state-of-the-art reviews, letters to the editor, meeting reviews) devoted to important advances in the rapidly changing fields of growth factor and cytokine research. Major emphasis is placed on the multidisciplinary significance of cytokines and growth factors in areas as diverse as signal transduction, cell growth and differentiation, embryonic development, immunology, tumorigenesis and clinical medicine. http://www.cgfr.co.uk//inpress?rss=yesElsevier Inc.en © 2011 Elsevier Ltd. All rights reserved. Cytokine & Growth Factor Reviews1359-61012012-01-11 © 2011 Elsevier Ltd. All rights reserved. healthpermissions@elsevier.comhttp://www.cgfr.co.uk/article/PIIS1359610111000712/abstract?rss=yesAbstract: Braking B cell tolerance to generate antibodies against autologous cytokines or chemokines offers an alternative to gene inactivation for functional analysis of these factors in vivo. It is clearly less potent than the genetic approach but offers the advantage of extreme flexibility. The basic principle is to enable a self-reactive B cell to attract T cell help by presenting foreign peptides, a process we called “deceptive” antigen presentation. We here review the different auto-vaccine procedures that are currently used and provide several examples of functional information acquired by this procedure or by mAbs derived from auto-vaccinated mice.Anti-cytokine auto-vaccinations as tools for the analysis of cytokine function in vivo - Corrected ProofCatherine Uyttenhove, Jacques Van Snick10.1016/j.cytogfr.2011.12.001Cytokine & Growth Factor Reviews (2012)2012-01-11Cytokine & Growth Factor Reviews2012-01-11MINI REVIEW