« Previous
Next »
Cytokine & Growth Factor Reviews
Volume 21, Issue 4
, Pages 263-273
, August 2010
High avidity cytokine autoantibodies in health and disease: Pathogenesis and mechanisms
References
- . Patient with circulating antibodies to alpha-interferon. Lancet. 1981;2:1227–1228
- . Interferon-neutralizing antibodies in a patient treated with human fibroblast interferon. Nature. 1981;289:496–497
- Interleukin-1-inhibitory IgG in sera from some patients with rheumatoid arthritis. Arthritis Rheum. 1989;32:1528–1538
- . IgG autoantibodies against interleukin 1 alpha in sera of normal individuals. Scand J Immunol. 1989;29:489–492
- . High-avidity autoantibodies to cytokines. Immunol Today. 1998;19:209–211
- . Binding of cytokines to pharmaceutically prepared human immunoglobulin. J Clin Invest. 1993;92:2533–2539
- Antibody to granulocyte-macrophage colony-stimulating factor is a dominant anti-cytokine activity in human IgG preparations. Blood. 1998;91:2054–2061
- . High avidity IFN-neutralizing antibodies in pharmaceutically prepared human IgG. J Clin Invest. 1995;95:1974–1978
- . Increased in vivo antibody activity against interferon alpha, interleukin-1alpha, and interleukin-6 after high-dose Ig therapy. Blood. 1997;90:2376–2380
- Idiopathic pulmonary alveolar proteinosis as an autoimmune disease with neutralizing antibody against granulocyte/macrophage colony-stimulating factor. J Exp Med. 1999;190:875–880
- Serological diagnosis of idiopathic pulmonary alveolar proteinosis. Am J Respir Crit Care Med. 2000;162:658–662
- Granulocyte/macrophage-colony-stimulating factor autoantibodies and myeloid cell immune functions in healthy subjects. Blood. 2009;113:2547–2556
- Anti-cytokine autoantibodies are ubiquitous in healthy individuals. FEBS Lett. 2007;581:2017–2021
- GM-CSF autoantibodies and neutrophil dysfunction in pulmonary alveolar proteinosis. N Engl J Med. 2007;356:567–579
- . Anti-interleukin-8 autoantibodies in patients at risk for acute respiratory distress syndrome. Crit Care Med. 2002;30:2335–2337
- . Anti-interleukin 8 autoantibody: interleukin 8 complexes in the acute respiratory distress syndrome. Relationship between the complexes and clinical disease activity. Am J Respir Crit Care Med. 2001;163:463–468
- High-affinity autoantibodies specifically eliminate granulocyte-macrophage colony-stimulating factor activity in the lungs of patients with idiopathic pulmonary alveolar proteinosis. Blood. 2004;103:1089–1098
- Detection of anti-interferon-gamma autoantibodies in subjects infected by Mycobacterium tuberculosis. Int J Tuberc Lung Dis. 1998;2:62–68
- . Cytokine autoantibodies in multiple sclerosis, aseptic meningitis and stroke. Eur J Clin Invest. 1998;28:295–299
- . Interleukin-8 and anti-interleukin-8 autoantibodies in gingival crevicular fluid from patients with periodontitis. J Periodontal Res. 2003;38:73–78
- . Evidence that natural autoantibodies against the nerve growth factor (NGF) may be potential carriers of NGF. J Neuroimmunol. 1997;75:200–203
- Anti-IL-8 autoantibodies in alveolar fluid from patients with the adult respiratory distress syndrome. J Immunol. 1996;157:2699–2706
- . Autoantibodies against granulocyte colony-stimulating factor in Felty's syndrome and neutropenic systemic lupus erythematosus. Arthritis Rheum. 2002;46:2384–2391
- Combined pure red cell aplasia and autoimmune hemolytic anemia in systemic lupus erythematosus with anti-erythropoietin autoantibodies. Am J Hematol. 2008;83:750–752
- Anti-IFN-gamma autoantibodies in disseminated nontuberculous mycobacterial infections. J Immunol. 2005;175:4769–4776
- Recurrent staphylococcal cellulitis and subcutaneous abscesses in a child with autoantibodies against IL-6. J Immunol. 2008;180:647–654
- Anti-interferon autoantibodies in autoimmune polyendocrinopathy syndrome type 1. PLoS Med. 2006;3:e289
- . Autoantibodies against interleukin 1alpha in rheumatoid arthritis: association with long term radiographic outcome. Ann Rheum Dis. 2002;61:598–602
- . High levels of neutralizing autoantibodies against IL-1 alpha are associated with a better prognosis in chronic polyarthritis: a follow-up study. Scand J Immunol. 1997;46:413–418
- . Reduced anti-TNFalpha autoantibody levels coincide with flare in systemic lupus erythematosus. J Autoimmun. 2004;22:315–323
- . Proinflammatory activity of anti-IL-8 autoantibody:IL-8 complexes in alveolar edema fluid from patients with acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2004;286:L1105–L1113
- IL-6-anti-IL-6 autoantibody complexes with IL-6 activity in sera from some patients with systemic sclerosis. J Immunol. 1994;152:935–942
- . High levels of neutralizing IL-6 autoantibodies in 0.1% of apparently healthy blood donors. Eur J Immunol. 2004;34:3267–3275
- . Pulmonary alveolar proteinosis. N Engl J Med. 2003;349:2527–2539
- Recommendations on haematological criteria for the diagnosis of epoetin-induced pure red cell aplasia. Eur J Haematol. 2004;73:389–396
- Pure red-cell aplasia and antierythropoietin antibodies in patients treated with recombinant erythropoietin. N Engl J Med. 2002;346:469–475
- . Autoantibodies to human recombinant erythropoietin in patients with systemic lupus erythematosus: correlation with anemia. Arthritis Rheum. 1997;40:2212–2216
- . Autoantibodies against erythropoietin in a patient with pure red-cell aplasia. N Engl J Med. 1996;334:630–633
- Autoantibodies to interferon-gamma in a patient with selective susceptibility to mycobacterial infection and organ-specific autoimmunity. Clin Infect Dis. 2004;38:e10–e14
- Naturally occurring anti-IFN-gamma autoantibody and severe infections with Mycobacterium cheloneae and Burkholderia cocovenenans. Blood. 2004;103:673–675
- . Disseminated Mycobacterium avium complex infection in a patient with autoantibody to interferon-gamma. Intern Med. 2007;46:1005–1009
- . Clinical variation of autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) in a series of 68 patients. N Engl J Med. 1990;322:1829–1836
- . Autoimmune polyendocrine syndromes. N Engl J Med. 2004;350:2068–2079
- . Aire. Annu Rev Immunol. 2009;27:287–312
- Anti-interleukin-6 autoantibodies in plasma are associated with an increased frequency of infections and increased mortality of patients with alcoholic cirrhosis. Scand J Immunol. 1996;44:623–629
- . Anti-interleukin-8 autoantibody:interleukin-8 immune complexes in acute lung injury/acute respiratory distress syndrome. Clin Sci (Lond). 2008;114:403–412
- . Anti-IL-8 autoantibody:IL-8 immune complexes suppress spontaneous apoptosis of neutrophils. Am J Physiol Lung Cell Mol Physiol. 2007;293:L364–L374
- Anti-interleukin-6 autoantibodies in rheumatic diseases. Increased frequency in the sera of patients with systemic sclerosis. Arthritis Rheum. 1992;35:940–943
- . Presence of interferon and anti-interferon in patients with systemic lupus erythematosus. Rheumatol Int. 1988;8:225–230
- Anti-cytokine autoantibodies in autoimmunity: preponderance of neutralizing autoantibodies against interferon-alpha, interferon-omega and interleukin-12 in patients with thymoma and/or myasthenia gravis. Clin Exp Immunol. 2003;132:128–136
- Naturally occurring anti-interferon-alpha 2a antibodies in patients with acute viral hepatitis. Clin Exp Immunol. 1991;85:80–84
- Autoantibodies to TNFalpha in HIV-1 infection: prospects for anti-cytokine vaccine therapy. Biomed Pharmacother. 2001;55:23–31
- . Detection of anti-interferon-alpha 2a antibodies in chronic liver disease. J Gastroenterol Hepatol. 1989;4:411–418
- . Individuals infected with HIV possess antibodies against IL-2. Immunology. 1988;65:611–615
- . Thymoma and thymic carcinoma: an update of the WHO Classification 2004. Surg Today. 2005;35:805–811
- Spontaneous production of anti-IFN-alpha and anti-IL-12 autoantibodies by thymoma cells from myasthenia gravis patients suggests autoimmunization in the tumor. Int Immunol. 2003;15:903–913
- . Do titin and cytokine antibodies in MG patients predict thymoma or thymoma recurrence?. Neurology. 2001;57:1579–1582
- . Interferon-producing cells: on the front line in immune responses against pathogens. Curr Opin Immunol. 2002;14:373–379
- Human thymus contains IFN-alpha-producing CD11c(−), myeloid CD11c(+), and mature interdigitating dendritic cells. J Clin Invest. 2001;107:835–844
- Sex- and age-dependency of IgG auto-antibodies against IL-1 alpha in healthy humans. Eur J Clin Invest. 1994;24:212–218
- . Age-related increase of autoantibodies to interleukin 1 alpha in healthy Japanese blood donors. J Med Invest. 1997;44:89–94
- . Distribution and characterization of autoantibodies to interleukin 1 alpha in normal human sera. Scand J Immunol. 1990;32:695–701
- . High-affinity IgG autoantibodies to IL-6 in sera of normal individuals are competitive inhibitors of IL-6 in vitro. Cytokine. 1993;5:72–80
- . Naturally occurring and therapy-induced antibodies to human granulocyte colony-stimulating factor (G-CSF) in human serum. J Cell Physiol. 1997;173:219–226
- Naturally-occurring anti-G-CSF antibodies produced by human cord blood B-cell lines infected with Epstein-Barr virus. Hematol J. 2001;2:161–171
- Antibodies binding granulocyte-macrophage colony stimulating factor produced by cord blood-derived B cell lines immortalized by Epstein–Barr virus in vitro. Cell Immunol. 2000;204:114–127
- The detection and biological activity of human antibodies to IL-2 in normal donors. Scand J Immunol. 1993;38:472–476
- . Serum levels of granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor in treated patients with chronic myelogenous leukemia in chronic phase. Haematologica. 1994;79:7–12
- Neutrophil attractant protein-1-immunoglobulin G immune complexes and free anti-NAP-1 antibody in normal human serum. J Clin Invest. 1992;90:471–481
- Generation and characterization of a human monoclonal autoantibody that acts as a high affinity interleukin-1 alpha specific inhibitor. Mol Immunol. 1996;33:649–658
- . Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor. Proc Natl Acad Sci U S A. 1990;87:9655–9659
- Cloning the interleukin 1 receptor from human T cells. Proc Natl Acad Sci U S A. 1989;86:8946–8950
- . Molecular cloning and expression of an IL-6 signal transducer, gp130. Cell. 1990;63:1149–1157
- . Molecular basis of the membrane-anchored and two soluble isoforms of the human interleukin 5 receptor alpha subunit. Proc Natl Acad Sci U S A. 1992;89:7041–7045
- . Expression cloning and characterization of a human IL-10 receptor. J Immunol. 1994;152:1821–1829
- . Ligand-induced association of the type I interferon receptor components. Mol Cell Biol. 1995;15:4208–4214
- Purification of interleukin-2 antibodies from healthy individuals. Immunol Lett. 1993;36:261–266
- . Autoantibodies to crude human leucocyte interferon (IFN), native human IFN, recombinant human IFN-alpha 2b and human IFN-gamma in healthy blood donors. Clin Exp Immunol. 1990;82:57–62
- . An anti-IL-2 antibody increases serum half-life and improves anti-tumor efficacy of human recombinant interleukin-2. Immunopharmacology. 1994;28:223–232
- Anti-cytokine antibodies as carrier proteins. Prolongation of in vivo effects of exogenous cytokines by injection of cytokine-anti-cytokine antibody complexes. J Immunol. 1993;151:1235–1244
- Enhancement of anti-tumor activity of recombinant interleukin-2 (rIL-2) by immunocomplexing with a monoclonal antibody against rIL-2. Biotherapy. 1993;6:225–231
- . Selective stimulation of T cell subsets with antibody-cytokine immune complexes. Science. 2006;311:1924–1927
- High levels of granulocyte and granulocyte-macrophage colony-stimulating factors in cord blood of normal full-term neonates. J Pediatr. 1990;116:627–632
- . Cellular and genetic mechanisms of self tolerance and autoimmunity. Nature. 2005;435:590–597
- Induction of anti-recombinant human granulocyte-macrophage colony-stimulating factor (Escherichia coli-derived) antibodies and clinical effects in nonimmunocompromised patients. Blood. 1994;84:4078–4087
- . Subcutaneous recombinant interleukin 2 in a dose escalating regimen in patients with metastatic renal cell adenocarcinoma. Cancer Res. 1990;50:6708–6715
- . Epoetin-induced autoimmune pure red cell aplasia. J Am Soc Nephrol. 2005;16(Suppl. 1):S67–S69
- Serial immunoprecipitation assays for interferon—(IFN)-beta antibodies in multiple sclerosis patients. Eur Cytokine Netw. 2003;14:154–157
- . The cellular mechanism of Aire control of T cell tolerance. Immunity. 2005;23:227–239
- Projection of an immunological self shadow within the thymus by the aire protein. Science. 2002;298:1395–1401
- . One step ahead of the game: viral immunomodulatory molecules. Annu Rev Immunol. 1996;14:101–130
- . Levels of gamma interferon and interleukin-4 are inversely related to the levels of their corresponding autoantibodies in patients with lower respiratory tract infection. Infect Immun. 1999;67:3051–3054
- . Anti-interleukin-6 and soluble interleukin-6 receptor in systemic lupus erythematosus. Lupus. 1994;3:161–166
- Circulating IL-8 and anti-IL-8 autoantibody in patients with ovarian cancer. Gynecol Oncol. 2006;102:244–251
- . Autoantibodies to IL-12 in myasthenia gravis patients with thymoma; effects on the IFN-gamma responses of healthy CD4+ T cells. J Neuroimmunol. 2003;139:102–108
- . Auto-antibodies to tumour necrosis factor alpha in healthy humans and patients with inflammatory diseases and gram-negative bacterial infections. Scand J Immunol. 1989;30:219–223
- . Comparison of anti-TNF alpha autoantibodies in plasma and from EBV transformed lymphocytes of autoimmune and normal individuals. Hum Antibodies Hybridomas. 1995;6:73–76
- Characteristics of a large cohort of patients with autoimmune pulmonary alveolar proteinosis in Japan. Am J Respir Crit Care Med. 2008;177:752–762
- Spontaneously occurring neutralizing antibodies against granulocyte-macrophage colony-stimulating factor in patients with autoimmune disease. Immunology. 1999;97:526–532
- . Incidence of autoantibodies against type I and type II interferons in a cohort of systemic lupus erythematosus patients in Slovakia. J Interferon Cytokine Res. 2003;23:143–147
- Induction of neutralizing autoantibodies to interferon-gamma in patients with polyneuropathy. Hum Antibodies. 1999;9:55–60
- . Autoantibodies to nerve growth factor in disorders of mental development in infants. Neurosci Behav Physiol. 2001;31:165–167
PII: S1359-6101(10)00028-6
doi: 10.1016/j.cytogfr.2010.03.003
© 2010 Elsevier Ltd. All rights reserved.
« Previous
Next »
Cytokine & Growth Factor Reviews
Volume 21, Issue 4
, Pages 263-273
, August 2010
