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Cytokine & Growth Factor Reviews
Volume 21, Issue 2
, Pages 161-167
, April 2010
A call to arms: Using RNAi screening to improve oncolytic viral therapy
References
- . Oncolytic viruses in cancer therapy. Cancer Lett. 2007;254:178–216
- . Principles of cancer therapy: oncogene and non-oncogene addiction. Cell. 2009;136:823–837
- Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus. Nat Med. 2000;6:821–825
- . Reovirus therapy of tumors with activated Ras pathway. Science. 1998;282:1332–1334
- VSV strains with defects in their ability to shutdown innate immunity are potent systemic anti-cancer agents. Cancer Cell. 2003;4:263–275
- . Virus–host interactions: from systems biology to translational research. Curr Opin Microbiol. 2009;12:432–438
- . What have RNAi screens taught us about viral–host interactions?. Curr Opin Microbiol. 2009;12:446–452
- . Building mammalian signalling pathways with RNAi screens. Nat Rev Mol Cell Biol. 2006;7:177–187
- Genome-scale RNAi screen for host factors required for HIV replication. Cell Host Microbe. 2008;4:495–504
- Identification of host proteins required for HIV infection through a functional genomic screen. Science. 2008;319:921–926
- Global analysis of host–pathogen interactions that regulate early-stage HIV-1 replication. Cell. 2008;135:49–60
- . A genome-wide short hairpin RNA screening of Jurkat T-cells for human proteins contributing to productive HIV-1 replication. J Biol Chem. 2009;284:19463–19473
- The IFITM proteins mediate cellular resistance to Influenza A H1N1 Virus, West Nile Virus, and Dengue Virus. Cell. 2009;139:1243–1254
- A Physical and regulatory map of host–influenza interactions reveals pathways in H1Ni infection. Cell. 2009;139
- Haploid genetic screens in human cells identify host factors used by pathogens. Science. 2009;326:1231–1235
- Drosophila RNAi screen identifies host genes important for influenza virus replication. Nature. 2008;454:890–893
- Human host factors required for influenza virus replication. Nature. 2009;
- Identification of host genes involved in hepatitis C virus replication by small interfering RNA technology. Hepatology. 2007;45:1413–1421
- Cellular cofactors affecting hepatitis C virus infection and replication. Proc Natl Acad Sci USA. 2007;104:12884–12889
- Roles for endocytic trafficking and phosphatidylinositol 4-kinase III alpha in hepatitis C virus replication. Proc Natl Acad Sci USA. 2009;106:7577–7582
- . RNA interference and single particle tracking analysis of hepatitis C virus endocytosis. PLoS Pathog. 2009;5:e1000702
- RNA interference screen for human genes associated with West Nile virus infection. Nature. 2008;455:242–245
- Discovery of insect and human dengue virus host factors. Nature. 2009;458:1047–1050
- Genome-wide analysis of human kinases in clathrin- and caveolae/raft-mediated endocytosis. Nature. 2005;436:78–86
- . The RNAi revolution. Nature. 2004;430:161–164
- . RNAi and double-strand RNA. Genes Dev. 1999;13:139–141
- . Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature. 1998;391:806–811
- The sequence of the human genome. Science. 2001;291:1304–1351
- Initial sequencing and analysis of the human genome. Nature. 2001;409:860–921
- Genome sequence of the nematode C. elegans: a platform for investigating biology. Science. 1998;282:2012–2018
- The genome sequence of Drosophila melanogaster. Science. 2000;287:2185–2195
- . Functional genomic analysis of C. elegans chromosome I by systematic RNA interference. Nature. 2000;408:325–330
- Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature. 2003;421:231–237
- Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes. Nature. 2003;421:268–272
- . Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli. Nature. 2002;416:644–648
- Genome-wide survey of protein kinases required for cell cycle progression. Nature. 2004;432:980–987
- Genome-wide RNAi analysis of growth and viability in Drosophila cells. Science. 2004;303:832–835
- An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division. Nature. 2004;432:1036–1040
- A large-scale RNAi screen in human cells identifies new components of the p53 pathway. Nature. 2004;428:431–437
- Host cell factors in HIV replication: meta-analysis of genome-wide studies. PLoS Pathog. 2009;5:e1000437
- . Knockdown screens to knockout HIV-1. Cell. 2008;135:417–420
- A loss-of-function RNA interference screen for molecular targets in cancer. Nature. 2006;441:106–110
- . shRNA libraries and their use in cancer genetics. Nat Methods. 2006;3:701–706
- A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene. Cell. 2009;137:835–848
- Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cells. Cell. 2009;137:821–834
- . A genome-wide RNAi screen for Wnt/beta-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer. Proc Natl Acad Sci USA. 2008;105:9697–9702
- Median absolute deviation to improve hit selection for genome-scale RNAi screens. J Biomol Screen. 2008;13:149–158
- Statistical methods for analysis of high-throughput RNA interference screens. Nat Methods. 2009;6:569–575
PII: S1359-6101(10)00024-9
doi: 10.1016/j.cytogfr.2010.02.013
© 2010 Elsevier Ltd. All rights reserved.
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Cytokine & Growth Factor Reviews
Volume 21, Issue 2
, Pages 161-167
, April 2010
