Cytokine & Growth Factor Reviews
Volume 21, Issue 2 , Pages 149-151 , April 2010

GM-CSF-armed, replication-competent viruses for cancer

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  4. Senzer NN, Kaufman HL, Amatruda T, Nemunaitis M, Reid T, Daniels G, et al. Phase II clinical trial of a granulocyte-macrophage colony-stimulating factor—encoding, second-generation oncolytic herpesvirus in patients with unresectable metastatic melanoma. J Clin Oncol. 2009;27(December (34)):5763–5771
  5. Mastrangelo MJ, Maguire HC, Lattime EC. Intralesional vaccinia/GM-CSF recombinant virus in the treatment of metastatic melanoma. Adv Exp Med Biol. 2000;465:391–400
  6. Park BH, Hwang T, Liu TC, Sze DY, Kim JS, Kwon HC, et al. Use of a targeted oncolytic poxvirus, JX-594, in patients with refractory primary or metastatic liver cancer: a phase I trial. Lancet Oncol. 2008;9(June (6)):533–542[Epub 2008 May 19]
  7. McKiernan J, Lamm D, Meng M, Nemunaitis J, Arseneau J, Stephenson J, et al. Abstract: phase 1 study of single and multi-dose administration of intravesical CG0070 in patients with non-muscle invasive bladder cancer (NMIBC). In: Fifth International Meeting on Replicating Oncolytic Virus Therapeutics—Bannf. Canada. 2009;
  8. Dranoff G, Jaffee E, Lazenby A, Golumbek P, Levitsky H, Brose K, et al. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc Natl Acad Sci USA. 1993;90(April (8)):3539–3543
  9. Mittendorf EA, Sharma P. Mechanisms of T-cell inhibition: implications for cancer immunotherapy. Expert Rev Vaccines. 2010;9(January (1)):89–105

PII: S1359-6101(10)00013-4

doi: 10.1016/j.cytogfr.2010.02.002

Cytokine & Growth Factor Reviews
Volume 21, Issue 2 , Pages 149-151 , April 2010

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